Evidence To Practice

Clinical Practice Guidelines DB

Clinical Practice Guidelines DB

Domestic

Korean Medicine Clinical Practice Guideline for Type 2 Diabetes Mellitus

Background and goal

With the socio-economic development of Korea, the number of people with diabetes is increasing due to overeating, lack of exercise, and increased stress. Type 2 Diabetes Mellitus is a disease that accounts for more than 90% of all diabetes, and reduces quality of life because it often follows serious complications. So continuous management and prevention are important. Although various oriental medicine treatments are being performed for type 2 diabetes in clinical practice, there is still no domestic clinical treatment guideline for type 2 diabetes. Therefore, the clinical practice guideline (CPG) was developed so that doctors of korean medicine can smoothly apply this to treat type 2 diabetes patients in the primary clinical field.

Overview of Type 2 Diabetes Mellitus

Pre-diabetes (ICD-10 code; R73.0) is a high-risk group with a high possibility of progressing to diabetes, and is largely classified into impaired glucose tolerance and impaired fasting glucose.
Type 2 Diabetes Mellitus (ICD-10 code; E10.9, E11.9, E12.9, E13.9, E14.9) is defined as chronic state of hyperglycemia, caused by decreased insulin secretion or insulin tolerance. Occasionally, it does not show any specific clinical symptoms. But, when blood sugar rises rapidly, polydipsia, polyuria, and weight loss may occur, and sometimes fatigue and decreased visual loss may appear.
If the clinical symptoms of diabetes are clear, it is similar to ‘sogal(消渴)’ disease.

(1) Diagnosis criteria

Pre-diabetes (High risk of diabetes): It is defined as glycated hemoglobin (HbA1c) of 5.7~6.4%.
① Impaired fasting glucose (IFG): It is defined as glucose levels of 100 to 125mg/dL in fasting patients.
② Impaired glucose tolerance (IGT): It is defined as two-hour glucose levels of 140 to 199mg/dL on the 75-g oral glucose tolerance test.

Diagnosis criteria for type 2 diabetes were applied by WHO’s <1999 Classification and Diagnosis Criteria for Diabetes>.

① Glycated hemoglobin (HbA1c)≥6.5%
② Fasting (more than 8 hours) plasma glucose level≥126mg/dL
③ Plasma glucose≥200mg/dL 2hours after a 75g oral glucose load as in a glucose tolerance test (OGTT)
④ Random plasma glucose≥200mg/dL accompanied with clinical symptom
(polydipsia, polyuria, unexplained weight loss etc.)